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    Home / Keto Italian Sub Sandwich Casserole 🥪

    Keto Italian Sub Sandwich Casserole 🥪

    Cast Iron Keto
    by Cast Iron Keto
    Updated: Dec 13,2023
    5 Comments
    5 from 8 votes

    Jump to Recipe Print Recipe

    This Keto Italian Sub Sandwich Casserole has all your favorite sub-flavors and even a crispy bread topping! It's low-carb, gluten-free, and super easy to make. You're going to love it!

    Keto Italian Sub Sandwich Casserole on a grey plate with a fork in front
    Jump to:
    • Preparation and cooking overview
    • Chef's note
    • 🥪 Ingredients for this keto Italian sub sandwich casserole recipe
    • Ingredient substitutions
    • Additional ingredients
    • How to make Keto Italian Sub Sandwich Casserole: step-by-step guide
    • Cooking methods
    • Preparation steps
    • Cooking instructions
    • What to serve with keto sub sandwich casserole?
    • How to make it healthier?
    • Time-saving tips
    • What can I prepare ahead of time?
    • Storage and reheating instructions
    • Recipe wrap-up and conclusion
    • Frequently asked questions
    • 📖 Recipe

    Preparation and cooking overview

    Making this Keto Casserole Recipe is super easy, taking less than an hour. Prepare the crust using shredded mozzarella, almond flour, and other ingredients. Then, layer the crust with deli ham, salami, pepperoni, capicola, cheese, veggies, and seasonings. Bake in the oven for 25-30 minutes until the crust is golden brown. And it is done!

    Chef's note

    Mix and match your favorite veggies to add more color and nutrients to the casserole. Add some sliced mushrooms, spinach, or even roasted eggplant for a deliciously hearty and filling dish. This keto casserole is all about versatility!

    • Prep Time: 20 minutes
    • Cooking Time: 30 minutes
    • Total Time: 50 Minutes
    • Difficulty Level: Easy
    • Recipe Makes 6 Servings

    For more inspiration check out our Casseroles recipe.

    🥪 Ingredients for this keto Italian sub sandwich casserole recipe

    Let's make a Keto Italian Sandwich Casserole with these simple ingredients!

    Crust

    • 1 ½ cups shredded mozzarella part-skim / low moisture
    • ⅔ cup almond flour
    • 2 egg whites
    • 1 teaspoon xanthan gum, optional

    Casserole filling

    • ½ pound sliced deli ham
    • 8 slices salami
    • 8 slices pepperoni
    • 8 slices capicola
    • 13 slices provolone cheese
    • 1 bell pepper, thinly sliced
    • 2 Roma tomatoes, diced or sliced
    • 1 cup pitted black or kalamata olives
    • ¼ medium red onion, thinly sliced
    • ½ cup pickled banana peppers
    • 2 tablespoons olive oil
    • 1 tablespoon red wine vinegar
    • 1 tablespoon Italian seasoning

    Ingredient substitutions

    • Deli ham: Instead of deli ham, use thinly sliced roast beef or turkey breast for a different flavor profile.
    • Salami: Replace salami with slices of keto-friendly pepperoni or chorizo for a spicy kick.
    • Provolone cheese: If you prefer a different cheese, substitute provolone with keto-friendly options like cheddar, mozzarella, or Swiss cheese.
    • Pickled banana peppers: If you're not a fan of banana peppers, use pickled jalapeños or pepperoncini peppers for some tang and spice.

    Additional ingredients

    Want to jazz up the flavor profile of this recipe? Let's add some optional ingredients to have a delicious low-carb casserole!

    • Basil leaves: Add some basil leaves on top of the casserole before baking for a herbal note.
    • Sliced mushrooms: For mushroom lovers, we recommend thinly slicing cremini or button mushrooms and adding them to the filling.
    • Red pepper flakes: Add a sprinkle of crushed red pepper flakes if you enjoy a bit of heat.
    • Parmesan cheese: Finish off your casserole with a generous sprinkle of grated Parmesan cheese for an extra layer of savory goodness.

    Note: These additional ingredients are completely optional and not included in the original recipe. Feel free to get creative and experiment with different flavors to suit your preferences.

    How to make Keto Italian Sub Sandwich Casserole: step-by-step guide

    Cooking methods

    • Baking

    Preparation steps

    1. Gather all the ingredients.
    2. Measure the ingredients precisely as instructed.
    3. Slice the deli meat, bell pepper, and red onion.
    4. Dice the Roma tomatoes.

    Cooking instructions

    1. Preheat the oven to 400°F (200°C).
    2. In a medium mixing bowl, melt the mozzarella in the microwave for about 30 seconds.
    3. Stir in the remaining dough ingredients into the mozzarella.
    4. Roll into a ball and knead 1 or 2 times. Place the dough between 2 sheets of parchment paper.
    5. Roll the dough out to a 10.5" circle about ½" thick using a rolling pin.
    6. Layer the remaining ingredients into a 10.5" skillet in this order: ham, salami, pepperoni, capicola, 1⁄2 the provolone, bell pepper, tomato, olives, red onion, and banana peppers.
    7. Drizzle the olive oil, red wine vinegar, and Italian seasoning over the top, then top with the remaining cheese and the crust.
    8. Transfer to the oven and bake for 25-30 minutes until the crust is browned. Serve immediately.
    Keto Italian Sub Sandwich Casserole on a grey plate with a fork in front

    Chef's pro tip

    Keep a close eye on the casserole towards the end of the baking time, and remove it from the oven as soon as the crust turns golden brown. This ensures a perfectly crispy and flavorful outcome.

    What to serve with keto sub sandwich casserole?

    • Fresh green salad: A simple green salad like Kale Salad or Arugula Salad will add a refreshing twist to this delicious keto casserole.
    • Broccoli salad: Serve with Keto Broccoli Salad for a slight crunch.

    How to make it healthier?

    • Use low-sodium ingredients: Look for low-sodium deli meats, cheese, and olives. Season with herbs, spices, and other flavorings to enhance taste without relying on excessive salt.
    • Incorporate more veggies: Add additional veggies like spinach, kale, or mushrooms. This way you'll boost the overall nutritional profile and have extra fiber.

    Time-saving tips

    • Make the extra crust: Prepare a double batch of dough crust and freeze the extra portion. This way, you'll have the crust ready for future recipes.

    What can I prepare ahead of time?

    • Prepare the crust in advance: Prepare the crust dough ahead of time. Follow the recipe instructions to make the dough and then wrap it tightly in plastic wrap. Store it in the refrigerator until you're ready to assemble the casserole.

    Storage and reheating instructions

    Storage tips

    To keep the leftovers fresh, store them in an airtight container in the refrigerator, where they can stay good for up to 3-4 days. If you wish to freeze the keto sandwich casserole, it is possible, but keep in mind that the texture and taste may undergo slight changes. For the best experience, consume the frozen sandwich within 1-2 months.

    Reheating best practices

    • Microwave: Place a portion of the casserole on a microwave-safe dish, cover, and heat for 2-3 minutes (850W) [3-4 minutes (600W)], rotating the dish once for even heating.
    • Oven: Preheat the oven to 350°F (180°C). Place the casserole in an oven-safe dish, cover with foil, and heat for 15-20 minutes until warmed.
    • Stove: Transfer a portion of the casserole to a saucepan or skillet. Heat over medium heat, occasionally flipping, until thoroughly heated.

    Recipe wrap-up and conclusion

    Our Keto Italian Sub Sandwich Casserole is a mouthwatering delight with its layers of deli meats, cheese, and veggies. Each bite offers a taste explosion that will satisfy your cravings. So grab your fork and enjoy this simple keto dinner that is a gluten-free winner!

    Looking for more keto casserole recipes? Here are some delicious keto-friendly options!

    • Keto Jalapeno Popper Chicken Casserole
    • Chicken Bacon Ranch Casserole
    • Keto Tuna Casserole
    • Broccoli Casserole with Bacon
    • Keto Buffalo Chicken Casserole
    • Keto Cheeseburger Casserole
    • Keto Chicken Fajita Casserole
    • Keto Pizza Casserole
    • Keto Zucchini Casserole

    Frequently asked questions

    Absolutely! The recipe is already gluten-free since it uses almond flour for the crust.

    Absolutely! Feel free to add or swap vegetables based on your preference. Just ensure they are thinly sliced or diced for even cooking.

    You can store Keto Italian sandwich casserole in the refrigerator for 3-4 days. Ensure proper storage in airtight containers for best results.

    Yes, you can! Add any protein of your choice, like ground chicken, turkey, or pork. You can also add Chicken Tinga or shredded chicken for added flavor.

    📖 Recipe

    Keto Italian Sub Sandwich Casserole on a grey plate with a fork in front

    Italian Sub Sandwich Casserole

    This Keto Italian Sub Sandwich Casserole has all of your favorite sub flavors and even a crispy bread topping! It's low-carb, gluten-free, and super easy to make. You're going to love it!
    5 from 8 votes
    Print Rate Pin Recipe
    Course: Main Course
    Cuisine: Italian
    Keyword: casserole recipe, Italian sandwich casserole, keto casserole, low carb
    Prep Time: 20 minutes minutes
    Cook Time: 30 minutes minutes
    Total Time: 50 minutes minutes
    Servings: 6
    Calories: 581kcal

    Ingredients

    Crust

    • 1 ½ cups shredded mozzarella
    • ⅔ cup almond flour
    • 2 egg whites
    • 1 teaspoon xanthan gum optional

    Casserole filling

    • ½ pound sliced deli ham
    • 8 slices salami
    • 8 slices pepperoni
    • 8 slices capicola
    • 13 slices provolone cheese
    • 1 bell pepper thinly sliced
    • 2 Roma tomatoes diced or sliced
    • 1 cup pitted black or kalamata olives
    • ¼ medium red onion thinly sliced
    • ½ cup pickled banana peppers
    • 2 tablespoons olive oil
    • 1 tablespoon red wine vinegar
    • 1 tablespoon Italian seasoning
    US Customary - Metric

    Instructions

    • Preheat the oven to 400° F.
    • In a medium mixing bowl, melt the mozzarella in the microwave for about 30 seconds.
    • Stir in the remaining dough ingredients into the mozzarella.
    • Roll into a ball and knead 1 or 2 times. Place the dough between 2 sheets of parchment paper.
    • Roll the dough out to a 10.5" circle about ½" thick using a rolling pin.
    • Layer the remaining ingredients into a 10.5" skillet in this order: ham, salami, pepperoni, capicola, 1⁄2 the provolone, bell pepper, tomato, olives, red onion, and banana peppers.
    • Drizzle the olive oil, red wine vinegar, and Italian seasoning over the top, then top with the remaining cheese and the crust.
    • Transfer to the oven and bake for 25-30 minutes until the crust is browned. Serve immediately.

    Nutrition

    Nutrition Facts
    Italian Sub Sandwich Casserole
    Amount Per Serving
    Calories 581 Calories from Fat 399
    % Daily Value*
    Fat 44.3g68%
    Carbohydrates 10.4g3%
    Fiber 3.2g13%
    Protein 35.9g72%
    *

    Nutritional values are estimates only and do not include carbs from sugar alcohols.

    # Hashtag with us!Don't forget to mention @castiron_keto or tag #castironketo on Instagram with your creations! We love seeing what you're making.
    « Roasted Vegetable Gazpacho
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    Reader Interactions

    Comments

    1. Sureve Everus says

      December 04, 2022 at 11:17 pm

      5 stars
      Whole family loves this. I often use the topping for just making regular sandwiches on or to top other keto casseroles.

      Reply
    2. Allen says

      May 24, 2022 at 12:12 am

      I love this recipe!!! Flavor is amazing. My only issue is with the amount of moisture produced that has to be bled off. This isn’t my first rodeo and yet after placing all the water laden veggies in paper towels prior to assembly, I still get about a cup of liquid that has to be poured off. I realize that we are working with very fatty meats and that they are rendered in the casserole. I just think it should be mentioned, that’s all. Again, love the flavors!!! I miss my Italian subs and this fills the void.

      Reply
    3. Dottie says

      May 25, 2021 at 1:59 am

      5 stars
      We just love this! Reminds us of the baked hoagies from Pennsylvania. Flavor bomb and so easy to make. Thank you for this recipe!

      Reply
    4. Lisa says

      September 02, 2020 at 1:56 pm

      That looks fun and delicious!

      Reply
    5. Katie S. says

      July 17, 2020 at 3:02 am

      5 stars
      So good! We've made 3 of your recipes three nights in a row and hot dang they're delicious!

      Reply
    5 from 8 votes (5 ratings without comment)

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